LAUNCH Smarter Chemistry

Dan Wilson: Dow Cheminformatics

  • United States

Dow Cheminformatics

The Dow Chemical Company’s project focuses on integrated mechanistic predictors of acute toxicity. Here is how they describe their work: “We are developing a tiered framework wherein salient safety information for potential acute toxicity can be derived early in product development. We are (1) compiling large inventories of acute toxicity data, (2) systematically deriving and cataloguing potential mechanisms associated with such toxicity, and (3) using various structural profiling capabilities to screen chemicals for structural features associated with those mechanisms. We are developing a workflow that integrates implementing mechanistic screening approaches early in product assessment.”